COMPOSITION
Each ml contains
Gentamicin Sulphate BP
Eq. to Gentamicin 10mg/20mg/40mg
Methyl Paraben BP 0.18% W/V
(As preservative)
Propyl Paraben BP 0.02% W/V
(As preservative)
Water for Injection BP q.s.
CLINICAL PHARMACOLOGY
Pharmacodynamic properties
Pharmacotherapeutic group: Antibacterials for systemic use,
ATC Code: J01GB03
Gentamicin is a mixture of antibiotic substances produced by the growth of micromonospora
purpurea. It is bactericidal with greater antibacterial activity than streptomycin, neomycin or
kanamycin.
Gentamicin exerts a number of effects on cells of susceptible bacteria. It affects the integrity of
the plasma membrane and the metabolism of RNA, but its most important effects is inhibition of
protein synthesis at the level of the 30s ribosomal subunit.
Gentamicin Injection BP