COMPOSITION
Each 3ml contains:
Diclofenac Potassium BP 75mg
Cyanocobalamin BP 10mg
Betamethasone Sodium Phosphate BP 2mg
Water for Injection BP q.s.
CLINICAL PHARMACOLOGY
Pharmacodynamic properties
Diclofenac is a non-steroidal anti-inflammatory whose mechanism of action, like other
NSAIDs, is not fully understood. Its ability to inhibit prostaglandin synthesis participates in
its pharmacological action. Betamethasone is a glucocorticoid that suppresses inflammation
by multiple mechanisms, inhibits the production of various intermediates of the inflammatory
reaction, including vasoactive and chemotactic factors; decreases the secretion of lipolytic
and proteolytic enzymes; it produces less extravasation of leukocytes towards the areas of
injury and reduces fibrosis; finally, it also affects the number and the immune reactions
dependent on lymphocytes. Cyanocobalamin is essential for cell growth and replication. Its
derivative, Methylcobalamin, is required for the formation of methionine and S-adenosyl
methionine from homo cysteine. Cyanocobalamin deficiency can cause irreversible damage
to the Nervous System, observing progressive swelling of neurons with demyelination and
neuronal death.
INDUFLEX INJECTION