{"id":5965,"date":"2022-06-26T08:00:45","date_gmt":"2022-06-26T02:30:45","guid":{"rendered":"http:\/\/induspharma.in\/?p=5965"},"modified":"2022-10-08T22:53:22","modified_gmt":"2022-10-08T17:23:22","slug":"cefotaxime-for-injection","status":"publish","type":"post","link":"https:\/\/induspharma.in\/productslist\/cefotaxime-for-injection\/","title":{"rendered":"Cefotaxime for Injection"},"content":{"rendered":"
\n\t\t\t
\n\t\t\t\t\"\"\n\t\t\t<\/div>\n\t\t\t\t
\n\t\t\t\tCefotaxime 500mg\n\t\t\t\t<\/figcaption><\/figure>
\n\t\t\t
\n\t\t\t\t\"cefotaxime-for-injection-1g\"\n\t\t\t<\/div>\n\t\t\t\t
\n\t\t\t\tCefotaxime 1g\n\t\t\t\t<\/figcaption><\/figure>\n\t\t<\/div>\n\n

COMPOSITION
\nEach vial contains:
\nCefotaxime Sodium USP
\nCefotaxime 1g
\nCLINICAL PHARMACOLOGY
\nPharmacodynamic properties
\nPharmacotherapeutic group: Beta-lactam antibiotics, cephalosporins.
\nATC Code: J01D D01
\nMode of action
\nCefotaxime exerts its action by binding to one or more of the penicillin-binding proteins (PBPs)
\nwhich in turn inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell
\nwalls, thereby inhibiting cell wall synthesis.
\nMechanisms of resistance
\nResistance to Cefotaxime may be due to one or several of the following mechanisms:
\n• production of extended-spectrum beta-lactamases (ESBLs)
\n• induction and\/or constitutive expression of AmpC beta- lactamases
\n• reduced outer membrane permeability
\n• efflux pump mechanisms.
\n• Modification of target enzymes (altered PBPs)
\nMore than one of these mechanisms may co-exist in a single bacterium.
\nPK\/PD relationship
\nEfficacy mainly depends on time above the minimal inhibitory concentration of cefotaxime for
\nthe pathogen(s) to be treated (T\/MIC).<\/p>\n

\nCefotaxime for Injection USP 1g<\/a>\n","protected":false},"excerpt":{"rendered":"

COMPOSITION Each vial contains: Cefotaxime Sodium USP Cefotaxime 1g CLINICAL PHARMACOLOGY Pharmacodynamic properties Pharmacotherapeutic group: Beta-lactam antibiotics, cephalosporins. ATC Code: J01D D01 Mode of action Cefotaxime exerts its action by binding to one or more of the penicillin-binding proteins (PBPs) which in turn inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls,…<\/p>\n","protected":false},"author":1,"featured_media":6380,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"_links":{"self":[{"href":"https:\/\/induspharma.in\/productslist\/wp-json\/wp\/v2\/posts\/5965"}],"collection":[{"href":"https:\/\/induspharma.in\/productslist\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/induspharma.in\/productslist\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/induspharma.in\/productslist\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/induspharma.in\/productslist\/wp-json\/wp\/v2\/comments?post=5965"}],"version-history":[{"count":5,"href":"https:\/\/induspharma.in\/productslist\/wp-json\/wp\/v2\/posts\/5965\/revisions"}],"predecessor-version":[{"id":6387,"href":"https:\/\/induspharma.in\/productslist\/wp-json\/wp\/v2\/posts\/5965\/revisions\/6387"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/induspharma.in\/productslist\/wp-json\/wp\/v2\/media\/6380"}],"wp:attachment":[{"href":"https:\/\/induspharma.in\/productslist\/wp-json\/wp\/v2\/media?parent=5965"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/induspharma.in\/productslist\/wp-json\/wp\/v2\/categories?post=5965"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/induspharma.in\/productslist\/wp-json\/wp\/v2\/tags?post=5965"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}