{"id":5953,"date":"2022-06-26T07:48:29","date_gmt":"2022-06-26T02:18:29","guid":{"rendered":"http:\/\/induspharma.in\/?p=5953"},"modified":"2022-12-26T16:25:06","modified_gmt":"2022-12-26T10:55:06","slug":"atracurium-besylate-injection","status":"publish","type":"post","link":"https:\/\/induspharma.in\/productslist\/atracurium-besylate-injection\/","title":{"rendered":"Atracurium Besylate Injection"},"content":{"rendered":"

Atracurium Besylate Injection<\/a> USP 10mg\/ml
\nCOMPOSITION
\nEach ml contains:
\nAtracurium Besylate USP 10mg
\nWater for Injection USP q.s.
\nCLINICAL PHARMACOLOGY
\nPharmacodynamic properties
\nPharmacotherapeutic group: muscle relaxants, peripherally acting agents; Other quaternary
\nammonium components
\nATC code: M03AC04
\nAtracurium besilate 10 mg\/ml is a non-depolarising muscle relaxant with medium duration of
\naction.
\nThe active substance, atracurium besilate, interacts specifically with neurophysiological
\nprocesses at the motor end-plate by competitively displacing acetylcholine from its receptor
\nsites.
\nAs a result of end-plate occupation by atracurium besilate, further depolarisation is inhibited.
\nSubsequently, skeletal muscles are paralysed since stimulation by motor nerves cannot be
\ntransmitted to the muscles.
\nThrough inhibition of acetylcholine degradation by means of cholinesterase inhibitors, e.g.
\nneostigmine or edrophonium, an increase of acetylcholine concentration is achieved at all
\ncholinergic synapses. The balance between atracurium besilate (antagonist) and acetylcholine
\n(agonist) is shifted in favour of the latter. As a result, stimulation of the muscle can reoccur.
\nPaediatric population:
\nThe limited data in neonates from literature reports suggest variability in the time to onset and
\nduration of atracurium in this population as compared to children<\/p>\n

\n

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\nAtracurium Besylate Injection USP 10mgml<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Atracurium Besylate Injection USP 10mg\/ml COMPOSITION Each ml contains: Atracurium Besylate USP 10mg Water for Injection USP q.s. CLINICAL PHARMACOLOGY Pharmacodynamic properties Pharmacotherapeutic group: muscle relaxants, peripherally acting agents; Other quaternary ammonium components ATC code: M03AC04 Atracurium besilate 10 mg\/ml is a non-depolarising muscle relaxant with medium duration of action. The active substance, atracurium besilate,…<\/p>\n","protected":false},"author":1,"featured_media":6340,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"_links":{"self":[{"href":"https:\/\/induspharma.in\/productslist\/wp-json\/wp\/v2\/posts\/5953"}],"collection":[{"href":"https:\/\/induspharma.in\/productslist\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/induspharma.in\/productslist\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/induspharma.in\/productslist\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/induspharma.in\/productslist\/wp-json\/wp\/v2\/comments?post=5953"}],"version-history":[{"count":5,"href":"https:\/\/induspharma.in\/productslist\/wp-json\/wp\/v2\/posts\/5953\/revisions"}],"predecessor-version":[{"id":6423,"href":"https:\/\/induspharma.in\/productslist\/wp-json\/wp\/v2\/posts\/5953\/revisions\/6423"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/induspharma.in\/productslist\/wp-json\/wp\/v2\/media\/6340"}],"wp:attachment":[{"href":"https:\/\/induspharma.in\/productslist\/wp-json\/wp\/v2\/media?parent=5953"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/induspharma.in\/productslist\/wp-json\/wp\/v2\/categories?post=5953"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/induspharma.in\/productslist\/wp-json\/wp\/v2\/tags?post=5953"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}