CLINICAL PHARMACOLOGY
Pharmacodynamic properties
Pharmacotherapeutic group : Anticholinesterases
ATC code: N07AA01
Neostigmine inhibits cholinesterase activity and prolongs and intensifies the muscarinic and
nicotinic effects of acetylcholine. The anticholinesterase actions of Neostigmine are reversible. It
is used mainly for its action on skeletal muscle and less frequently to increase the activity of
smooth muscle. Neostigmine is used in the treatment of Myasthenia Gravis.
Neostigmine Injection BP 0.5mgml &2.5mgml