COMPOSITION
Each ml contains
Amikacin Sulphate BP
Eq. to Amikacin 25mg/50mg/125mg/250mg
Methyl Paraben BP 0.1%w/v
Propyl Paraben BP 0.02%w/v
Water for Injection BP q.s.
CLINICAL PHARMACOLOGY
Pharmacodynamic properties
Pharmacotherapeutic group: Aminoglycoside antibiotic.
ATC code: J01G B06
Amikacin is a semi-synthetic aminoglycoside antibiotic derived from Kanamycin A. It is active against a broad spectrum of Gram-negative organisms, including pseudomonas, Escherichia coli and some Gram-positive organisms, e.g. Staphylococcus aureus.
Aminoglycoside antibiotics are bactericidal in action. Although the exact mechanism of action has not been fully elucidated, the drugs appear to inhibit protein synthesis in susceptible bacteria by irreversibly binding to 30S ribosomal subunits
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Amikacin Injection BP-converted