Each ml contains:
Ketorolac Tromethamine USP
Eq. to Ketorolac 30mg
Sodium Chloride USP 4.3mg
Benzyl Alcohol USP 2% w/v
Water for Injection USP q.s
Pharmacotherapeutic group: Antiinflammatory and antirheumatic products, acetic acid derivatives and related substances
ATC Code: M01AB15
Ketorolac is a potent analgesic agent of the non-steroidal, anti-inflammatory class (NSAID). It is not an opioid and has no known effects on opioid receptors. Its mode of action is to inhibit the cyclo-oxygenase enzyme system and hence prostaglandin synthesis, and it demonstrates a minimal anti-inflammatory effect at its analgesic dose.
IM: Following intramuscular administration, ketorolac Tromethamine was rapidly and completely absorbed, a mean peak plasma concentration of 2.2µ g/ml occurring an average of 50 minutes after a single 30mg dose. The influences of age, kidney and liver function on terminal plasma half-life and mean total clearance are outlined in the table below (estimated from a single 30mg IM dose of ketorolac).
readKetorolac Tromethamine Injection USP 60mg2ml