COMPOSITION Each ml contains
Clindamycin Phosphate USP
Eq. to Clindamycin 150 mg, 300mg available
Benzyl Alcohol USP 9.45mg
Water for Injection USP q.s.
Pharmacotherapeutic group: Lincosamides
ATC code: J01FF01
Mechanism of action
Clindamycin is a lincosamide antibiotic with a primarily bacteriostatic action against Gram-positive aerobes and a wide range of anaerobic bacteria. Lincosamides such as clindamycin bind to the 50S subunit of the bacterial ribosome similarly to macrolides such as erythromycin and inhibit the early stages of protein synthesis. The action of clindamycin is predominantly bacteriostatic although high concentrations may be slowly bactericidal against sensitive strains. Although clindamycin phosphate is inactive in vitro, rapid in vivo hydrolysis converts this compound to the antibacterially active clindamycin.
Clindamycin Injection USP 150mgml-converted