Each ml contains
Adrenaline Acid Tartrate BP 1.8mg
Eq. to adrenaline 1mg
Sodium Chloride BP 7.3mg
Water for Injection BP q.s.
Pharmacotherapeutic group: adrenergic and dopaminergic agents, adrenaline.
ATC code: C01 CA 24
Adrenaline is a naturally occurring catecholamine secreted by the adrenal medulla in response to exertion or stress. It is a sympathomimetic amine which is a potent stimulant of both alpha- and beta-adrenergic receptors and its effects on target organs are therefore complex. It is used to provide rapid relief of hypersensitivity reactions to allergies or to idiopathic or exercise-induced anaphylaxis.
Adrenaline has a strong vasoconstrictor action through alpha- adrenergic stimulation. This activity counteracts the vasodilatation and increased vascular permeability leading to loss of intravascular fluid and subsequent hypotension, which are the major pharmacological features in anaphylactic shock.
Adrenaline stimulates bronchial beta-adrenergic receptors and has a powerful bronchodilator action. Adrenaline also alleviates pruritus, urticaria and angioedema associated with anaphylaxis.
ReadAdrenaline Injection BP 1mgml-converted